British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists.

Background/aims This study assesses the proficiency of Generative Pre-trained Transformer (GPT)-4 in answering questions about complex clinical ophthalmology cases. Methods We tested GPT-4 on 422 ...

Purpose Thyroid eye disease (TED) is a progressive, debilitating and potentially vision-threatening autoimmune disease. Teprotumumab, a novel human monoclonal antibody, has been shown to reverse the ...

Aim: To investigate the correlation between retinal nerve fibre layer (RNFL) thickness and optic nerve head (ONH) size in normal white subjects by means of optical coherence tomography (OCT). Methods: ...

Background UK estimates of age related macular degeneration (AMD) occurrence vary. Aims To estimate prevalence, number and incidence of AMD by type in the UK population aged ≥50 years. Methods ...

Background/aims To compare the performance and cost-effectiveness of DeepSeek-R1 with OpenAI o1 in diagnosing and managing ophthalmology clinical cases. Methods In this cross-sectional study, a total ...

Background Infectious keratitis (IK) predominantly affects patients from rural agrarian regions with limited access to medical care, leading to delayed presentation associated with poorer visual ...

Background/aims To compare fluctuations of central subfield retinal thickness (CSRT) in patients with neovascular age-related macular degeneration undergoing ranibizumab pro re nata versus aflibercept ...

Introduction Glaucoma is a lifelong condition often requiring surgical intervention. To allow us to inform patients’ expectations of surgery effectively, it is important to understand patients’ ...

Aims To investigate the prevalence and incidence of juvenile idiopathic arthritis (JIA)-associated uveitis (JIA-U) in the USA from 2013 to 2023 by analysing the TriNetX database. Secondary outcomes ...

### 2.1 - Primary Congenital Forms/Childhood Glaucomas Primary congenital glaucoma is a rare disease but has a major impact on the child’s development and quality of life over his/her whole life span.

We studied ocular surface pH in 161 subjects. The mean pH for 133 normal volunteers was 7 . 11, SD 1 . 5. We found that older women had a more alkaline pH than other subjects, that the pH shifted from ...