Head coach Kyle Shanahan told reporters at a Monday press conference that running back Isaac Guerendo is going to miss will ...

San Francisco 49ers WR Jauan Jennings hasn't practiced since July 27. One explanation is a calf injury with a vague recovery ...

Last year, the San Francisco 49ers saw their skill-position corps decimated by injuries. Star running back Christian ...

The 49ers may provide an indication of how they're feeling about their RB depth in the days ahead. If they sign another ...

It’s time for the San Francisco 49ers to reevaluate the running back position. The depth chart order behind Christian ...

The San Francisco 49ers seem to be off to a rough start with two concerning training camp injuries revealed by Kyle Shanahan.

San Francisco head coach Kyle Shanahan said Thursday that James will miss a couple weeks due to a broken finger, Cam Inman of The San Jose Mercury News reports. James will require surgery to address ...

Injuries forced running back Isaac Guerendo and fullback Kyle Juszczyk out of Saturday’s practice at 49ers training camp.

Stats and projections for Isaac Guerendo in fantasy football, including ADP, insights, and 2025 outlook, as the San Francisco ...

Discover the top breakout running backs for 2025 fantasy football drafts, including Jordan Mason, Isaac Guerendo, and Omarion ...

San Francisco 49ers running back Christian McCaffrey explained why he sometimes feels uneasy sleeping in a hotel room amid ...

Isaac Guerendo ’s mother, Jen, realized that early on. She remembers a family gathering at a park in southern Indiana during which the kids had a big race. Isaac was 5 or 6 at the time.