Jim Gaffigan shared his weight loss journey with Mounjaro, as he shed 50 pounds. Celebrities like Rosie O'Donnell and Amy Schumer also credited the diabetes drug.

Jim Gaffigan doesn’t want any credit for his 50-lb weight loss — no, seriously. ... The comic spoke exclusively to Us Weekly about his journey with Mounjaro in November 2024.

The comic previously told PEOPLE that he wanted to talk about taking the injectable Mounjaro, explaining, "I don't think there's anything wrong with it" Jim Gaffigan riffed about not being able to ...

Jim Gaffigan attends an event in NYC in 2017. As he previously told PEOPLE, Gaffigan lost 50 lbs. with the help of weight loss medication — specifically, Mounjaro .